生物谷

Nature：揭示H+转运是线粒体ADP/ATP载体发挥功能所必需的一种功能

2019年7月30日讯/生物谷BIOON/---一种称为线粒体的亚细胞结构是我们细胞的能量工厂。每天，人类需要身体产生ATP来为所有细胞 ...
生物通

线粒体基质pH动态成像揭示ADP/ATP载体与ATP合酶功能互作调控H+分布的 ...

本研究通过实时成像技术揭示ADP/ATP载体（AAC）与ATP合酶的功能性相互作用如何精确调控线粒体内膜H+流分布，为能量平衡失调 ...
生物通

人类SLC35B1介导ATP逐步转运进入内质网的分子机制与结构基础

本研究揭示了内质网ATP转运蛋白SLC35B1（原误认为核苷酸糖转运体）通过独特的逐步移位机制执行严格的ATP/ADP交换。研究人员 ...
Nature

AMPK: a nutrient and energy sensor that maintains energy homeostasis

AMP-activated protein kinase (AMPK) occurs as heterotrimeric protein complexes that monitor cellular energy status by sensing the concentrations of ATP, ADP and AMP. Displacement of ATP by ADP or AMP ...
EurekAlert!

Researchers create ADP- or ATP-containing molecules with improved yield and consistency

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
News Medical

Adenosine Triphosphate (ATP) Function in Cells

ATP is the main source of energy for most cellular processes. The building blocks of ATP are carbon, nitrogen, hydrogen, oxygen, and phosphorus. Because of the presence of unstable, high-energy bonds ...