Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and ...

Phase 1a/1b study in 97 patients demonstrates mitochondrial metabolic reprogramming induced by BPM31510-IV and supports advancement in multiple ...

In a systematic review published in Nutrients, researchers described gut microbiota and metabolic alterations common to metabolic syndrome (MetS) and sleep disorders. Study: The Microbiota–Gut–Brain ...

Diabetes mellitus, cardiovascular disease, and ageing represent major global health challenges. Diabetes and periodontal disease share a well-established ...

The plasticity of macrophages depends on the spatial distribution, surrounding cell types, external microenvironment and extrinsic stimuli. This represents not only their capability to rapidly adapt, ...

The liver plays a central role in maintaining systemic energy homeostasis during fasting by mobilizing lipid reserves, a ...

Chrononutrition research indicates that eating later in the evening or at night, when circadian physiology is less favorable ...

FGF19 triggers the brain to burn more energy and activate fat-burning cells, offering a potential new path for obesity ...

Melanie R. McReynolds receives funding from the Howard Hughes Medical Institute Hanna H. Gray Fellows Program Faculty Phase and the Burroughs Welcome Fund PDEP Transition to Faculty. Aging is a ...

Two of the traits that set modern humans apart from non-human primates are taller stature and a higher basal metabolic rate. Researchers have identified a genetic variant that contributed to the ...