Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Researchers at the Max Delbrück Center have developed an open-source spatial transcriptomics (ST) platform, called Open-ST, that creates 3D molecular maps from patient tissue samples with subcellular ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

Tumor purity as confounder for the determination of tumor mutational burden (TMB). This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...