聚焦2024ESC大会上ATTR-CA相关研究新进展，为临床ATTR-CA防治带来更多思考和借鉴。心脏淀粉样变（CA）是一种浸润性限制性心肌病，由体内可溶性蛋白 ...

ATTR-CM有两种亚型：遗传型TTR淀粉样变性心肌病，由转甲状腺素蛋白基因突变引起，患者发病年龄较早，为50-60岁左右；另一种为野生型TTR淀粉样变性 ...

Vutrisiran is also in development for the treatment of ATTR amyloidosis with cardiomyopathy (ATTR-CM), which encompasses both wild-type and hereditary forms of the disease.

Analyses from an ongoing, international, observational registry show that transthyretin (ATTR) amyloidosis variants F64L, I107V, and S77Y are typically associated with a neurologic phenotype.