A patient with type 1 diabetes received genetically modified allogeneic islets and no immunosuppression. Results obtained ...

In this phase 3b, open-label, controlled trial, adult participants with obesity but without type 2 diabetes were randomly assigned in a 1:1 ratio to receive the maximum tolerated dose of tirzepatide ...

The United States could take meaningful steps toward eliminating hepatitis C by broadly testing and treating people who are involved in the criminal legal system.

Explore the current issue of The New England Journal of Medicine (Vol. 395 No. 3).

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 5).

The authors describe the scientific foundations of a study of gene therapy for hearing loss caused by damaging variants in the gene OTOF. Department of Otorhinolaryngology and Head and Neck Surgery, ...

Aspirin after an initial short course of rivaroxaban has been shown to be safe and effective for the prevention of venous thromboembolism after total hip or total knee arthroplasty, but uncertainty ...

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity.In this phase 3, multinational, randomized, double ...

Two patients had autoimmune hemolytic anemia that relapsed after CD19 CAR T-cell therapy but responded rapidly to BCMA-targeted T-cell–engager therapy with remission, minimal side effects, and hema ...

An 80-year-old woman was admitted with pancytopenia. Five weeks earlier, nausea, vomiting, diarrhea, chills, and fever had developed. CT revealed bilateral pelvic masses; examination of a ...

In this trial of arthroscopic partial meniscectomy for degenerative medial meniscal tear in adults, participant-reported and radiologic outcomes over 10 years of follow-up suggested no benefit and ...

During the 6-year period, 7901 deaths occurred. The leading cause of maternal death was unintentional drug overdose (1152 deaths; 5.2 deaths per 100,000 live births). Violence (defined as homicide or ...