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今日Cell:深究肠道纤维化元凶 | 热心肠日报
① 研究设计与方法:本研究构建了人类克罗恩病(CD)成纤维细胞图谱,并通过整合单细胞测序、空间转录组学与细胞外基质(ECM)超微结构分析,结合可模拟爬行脂肪(CF)和肠道纤维化的小鼠模型,系统探究了CF在肠道纤维化中的作用。② ...
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