Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Allosteric compounds offer an alternative mode of inhibition to orthosteric compounds ...

Objective: This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as ...

Abstract: The K-Means algorithm in the clustering process has limitations when dealing with clusters that have undefined sizes and shapes. One way to overcome this weakness is by using another ...

Hippocampal pyramidal neurons exhibit diverse spike patterns and gene expression profiles. However, their relationships with single neurons are not fully understood. In this study, we designed an ...

Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr.-Bohr-Gasse 9, 1030 Vienna, Austria Center for Molecular Biology, Department of Biochemistry and Cell Biology, University ...

Low-dimensional linear dynamics are observed in neuronal population activity in primary motor cortex (M1) when monkeys make reaching movements. This population-level behavior is consistent with a role ...

Understanding the key drivers of animal movement is crucial to assist in mitigating adverse impacts of anthropogenic activities on marine megafauna. We found that movement patterns of marine megafauna ...

During rest, the human brain performs essential functions such as memory maintenance, which are associated with resting-state brain networks (RSNs) including the default-mode network (DMN) and ...

The discovery of hierarchy and community organization has always been considered a problem of determining the correct membership (or memberships) of each node. Notice that, whereas nodes belong to ...

The dendrograms produced by our method are also of interest in themselves, as a graphical representation and summary of the hierarchical structure of the observed network. As discussed above, our ...

The investigation of community structures in networks is an important issue in many domains and disciplines. This problem is relevant for social tasks (objective analysis of relationships on the web), ...